Gingival Tumescence and A Palatal Ulcer-A Case of AML with an Adverse Drug Reaction to Chemotherapy

Acute and chronic forms of leukemia may initially present with oral manifestations. These manifestations may include gingival swelling, petechiae, ecchymosis, gingival hemorrhage, mucosal pallor and oral infections (e.g., herpes simplex, Candidiasis). Treatment for leukemia may involve the use of chemotherapeutics, some of which are associated with adverse drug reactions which may also present with oral signs and symptoms. It is paramount for all health care providers to consider both local and systemic causes of oral manifestations in their differential diagnoses and to be cognizant of oral manifestations of adverse drug reactions.